diff --git a/packages/vite/src/node/config.ts b/packages/vite/src/node/config.ts
index d99d135447c045..57015dc4c356b3 100644
--- a/packages/vite/src/node/config.ts
+++ b/packages/vite/src/node/config.ts
@@ -483,21 +483,6 @@ export async function resolveConfig(
     customLogger: config.customLogger,
   })
 
-  let foundDiscouragedVariableName
-  if (
-    (foundDiscouragedVariableName = Object.keys(config.define ?? {}).find((k) =>
-      ['process', 'global'].includes(k),
-    ))
-  ) {
-    logger.warn(
-      colors.yellow(
-        `Replacing ${colors.bold(
-          foundDiscouragedVariableName,
-        )} using the define option is discouraged. See https://vitejs.dev/config/shared-options.html#define for more details.`,
-      ),
-    )
-  }
-
   // resolve root
   const resolvedRoot = normalizePath(
     config.root ? path.resolve(config.root) : process.cwd(),